Here’s the short answer to the title of this post: No.
But for a slightly longer answer, I’ll point out that many things could happen. Kim Reynolds could get caught driving drunk while cheating on her husband. Chuck Grassley could die from old age. And so on. But assuming nothing outrageous happens, Democrats won’t win the major federal or statewide races this fall. They will lose Iowa in 2022. Normal campaigning and GOTV efforts won’t be enough to win.
Incidentally, wealthier Democratic donors and party officials already know this. It’s a big part of why donors haven’t given as much money as usual by this point. A few progressives in the state have even criticized Democrats for ‘throwing in the towel.’